Stiripentol ( BCX2600 )

Catalog No. M18654 CAS No. 49763-96-4

Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59/0.516 μM and IC50 of 1.58/3.29 μM, respectively.

Purity : 98%

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Biological Information

Product Name

Stiripentol
Note

Research use only, not for human use.
Brief Description

Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59/0.516 μM and IC50 of 1.58/3.29 μM, respectively.
Description

Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59/0.516 μM and IC50 of 1.58/3.29 μM, respectively.
Synonyms

BCX2600
Pathway

Others
Target

Other Targets
Recptor

CYP3A4; CYP2C19
Research Area

——
Indication

——

Chemical Information

CAS Number

49763-96-4
Formula Weight

234.29
Molecular Formula

C14H18O3
Purity

98%
Solubility

DMSO : 150 mg/mL 640.23 mM;
SMILES

CC(C)(C)C(O)\C=C\c1ccc2OCOc2c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Giraud C, et al. In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism.Drug Metab Dispos. 2006 Apr;34(4):608-11. Epub 2006 Jan 13.

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