Stepronin

CAS No. 72324-18-6

Stepronin( —— )

Catalog No. M33732 CAS No. 72324-18-6

Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 41 Get Quote
10MG 65 Get Quote
25MG 109 Get Quote
50MG 191 Get Quote
100MG 291 Get Quote
200MG 410 Get Quote
500MG Get Quote Get Quote
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Biological Information

  • Product Name
    Stepronin
  • Note
    Research use only, not for human use.
  • Brief Description
    Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.
  • Description
    Stepronin (Prostenoglycine) is an orally active expectorant (inhalation administration is preferable to oral administration). Stepronin inhibits airway secretion in vitro by reducing Cl- secretion from epithelial cells and mucus glycoprotein secretion from submucosal glands.
  • In Vitro
    Stepronin (0.1-100 μM; 20 min) induces significant reductions in ISOP(Isoproterenol)-evoked SCC (short circuit current) value in a dose-dependent manner in canine tracheal epithelium.Stepronin (10-100 μM; 20 min) significantly inhibits the basal secretion and ISOP-evoked PD (potential difference) value in a dose-dependent manner in canine tracheal epithelium.Stepronin (100 μM; 20 min) significantly inhibits ISOP-induced [3H]-glycoconjugate secretion in submucosal glands.Cell Viability Assay Cell Line: Canine tracheal epithelium (from adult and 10 to 25 kg-weight mongrel dogs of both sexes)Concentration:0.1-100 μM; 10-100 μMIncubation Time:20 min (pre-treat) Result:Significantly inhibited ISOP-induced SCC and PD values, as well as basal secretion. Cell Viability Assay Cell Line:Submucosal glands (from adult and 10 to 25 kg-weight mongrel dogs of both sexes) Concentration:100 μM Incubation Time:20 min (pre-treat) Result:Significantly inhibited ISOP- induced [3H]-glycoconjugate secretion.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    72324-18-6
  • Formula Weight
    273.33
  • Molecular Formula
    C10H11NO4S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 250 mg/mL (914.65 mM)
  • SMILES
    CC(SC(=O)c1cccs1)C(=O)NCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yamada K, et al. An expectorant, stepronin, reduces airway secretion in vitro. Respiration. 1994;61(1):42-7. ?
molnova catalog
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