Spathulenol
CAS No. 6750-60-3
Spathulenol ( )
Catalog No. M31040 CAS No. 6750-60-3
Spathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway.
Purity : >98% (HPLC)
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5MG | 511 | In Stock |
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50MG | Get Quote | In Stock |
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Biological Information
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Product NameSpathulenol
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NoteResearch use only, not for human use.
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Brief DescriptionSpathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway.
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DescriptionSpathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway; it presents moderate or low cytotoxicity with IC50 higher than 6uM, it is a good candidate to be used in combination chemotherapy of MDR cancer.
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Synonyms
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number6750-60-3
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Formula Weight220.4
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Molecular FormulaC15H24O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CRSP-1
Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin receptors. Inhibits formation of multinuclear osteoclasts with similar efficacy to CT in vitro. Suppresses food intake and increases body temperature in free-feeding rats, and significantly decreases plasma calcium levels in vivo.
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SBE-β-CD
SBE-β-CD is a sulfobutylether β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether (SBE).
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16-Epivoacarpine
16-Epivoacarpine is a natural product from Gelsemium elegans.