Somatostatin-25

CAS No. 76461-17-1

Somatostatin-25( —— )

Catalog No. M30508 CAS No. 76461-17-1

Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic activities.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Somatostatin-25
  • Note
    Research use only, not for human use.
  • Brief Description
    Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic activities.
  • Description
    Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic activities. (In Vitro):Somatostatin-25 (0.1 pM-1 nM) significantly inhibits secretion of growth hormone in the in vitro system, and is 3-14 times more effective than the tetradecapeptide. Somatostatin-25 (0.1 nM-1pM) also inhibits secretion of growth hormone induced by the addition of prostaglandin 2 (PGE2). However, Somatostatin-25 shows no effect on the secretion of prolactin.
  • In Vitro
    Somatostatin-25 (0.1 pM-1 nM) significantly inhibits secretion of growth hormone in the in vitro system, and is 3-14 times more effective than the tetradecapeptide. Somatostatin-25 (0.1 nM-1pM) also inhibits secretion of growth hormone induced by the addition of prostaglandin 2 (PGE2). However, Somatostatin-25 shows no effect on the secretion of prolactin.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76461-17-1
  • Formula Weight
    2876.3
  • Molecular Formula
    C127H191N37O34S3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: Cys14-Cys25)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Brazeau P, et al. High biological activity of the synthetic replicates of somatostatin-28 and somatostatin-25. Regul Pept. 1981 Jan;1(4):255-64.
molnova catalog
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