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Smurf1-IN-A01
CAS No. 1007647-73-5
Smurf1-IN-A01 ( A01 )
Catalog No. M23212 CAS No. 1007647-73-5
Smurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 41 | In Stock |
|
| 5MG | 65 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 222 | In Stock |
|
| 50MG | 356 | In Stock |
|
| 100MG | 530 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSmurf1-IN-A01
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NoteResearch use only, not for human use.
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Brief DescriptionSmurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM).
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DescriptionSmurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
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SynonymsA01
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PathwayOthers
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TargetOther Targets
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RecptorSmurf1
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Research Area——
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Indication——
Chemical Information
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CAS Number1007647-73-5
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Formula Weight512.9
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Molecular FormulaC22H20ClF3N4O3S
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Purity>98% (HPLC)
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SolubilityDMSO:62.5 mg/mL (121.85 mM; Need ultrasonic)
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SMILESCC1=CC=NN1C2=CC=C(C=C2)C(=O)N3CCN(CC3)S(=O)(=O)C4=CC(=C(C=C4)Cl)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cao Y, et al. Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation. Sci Rep. 2014 May 14;4:4965.
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