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Skepinone-L

CAS No. 1221485-83-1

Skepinone-L( Skepinone-L )

Catalog No. M17201 CAS No. 1221485-83-1

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.

Purity : 98%

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	41	In Stock
5MG	65	In Stock
10MG	110	In Stock
25MG	197	In Stock
50MG	296	In Stock
100MG	440	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Skepinone-L
Note

Research use only, not for human use.
Brief Description

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
Description

Skepinone-L is an ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50s = 5 nM) and p38β (97% inhibition at 1 μM).
Synonyms

Skepinone-L
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

p38α
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

1221485-83-1
Formula Weight

425.42
Molecular Formula

C24H21F2NO4
Purity

98%
Solubility

DMSO : ≥ 50 mg/mL 117.53 mM; H2O : < 0.1 mg/mL
SMILES

c12c(C(=O)c3c(CC1)ccc(c3)OC[C@@H](CO)O)ccc(c2)Nc1c(cc(cc1)F)F
Chemical Name

2-[(2,4-difluorophenyl)amino]-7-[(2R)-2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Koeberle SC, et al. Nat Chem Biol. 2011, 8(2), 141-143.

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