Skepinone-L

CAS No. 1221485-83-1

Skepinone-L ( Skepinone-L )

Catalog No. M17201 CAS No. 1221485-83-1

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 65 In Stock
10MG 110 In Stock
25MG 197 In Stock
50MG 296 In Stock
100MG 440 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Skepinone-L
  • Note
    Research use only, not for human use.
  • Brief Description
    Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
  • Description
    Skepinone-L is an ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50s = 5 nM) and p38β (97% inhibition at 1 μM).
  • Synonyms
    Skepinone-L
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    p38α
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    1221485-83-1
  • Formula Weight
    425.42
  • Molecular Formula
    C24H21F2NO4
  • Purity
    98%
  • Solubility
    DMSO : ≥ 50 mg/mL 117.53 mM; H2O : < 0.1 mg/mL
  • SMILES
    c12c(C(=O)c3c(CC1)ccc(c3)OC[C@@H](CO)O)ccc(c2)Nc1c(cc(cc1)F)F
  • Chemical Name
    2-[(2,4-difluorophenyl)amino]-7-[(2R)-2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Koeberle SC, et al. Nat Chem Biol. 2011, 8(2), 141-143.
molnova catalog
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