Sirtinol

CAS No. 410536-97-9

Sirtinol ( Sirtinol )

Catalog No. M18528 CAS No. 410536-97-9

Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 32 In Stock
5MG 48 In Stock
10MG 77 In Stock
25MG 169 In Stock
50MG 324 In Stock
100MG 482 In Stock
500MG 1062 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Sirtinol
  • Note
    Research use only, not for human use.
  • Brief Description
    Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
  • Description
    Sirtinol is a SIRT inhibitor. Sirtinol significantly increased the acetylation of p53, which has been reported to be a target of SIRT1/2. Sirtinol significantly increased the G1 phase of the cell cycle.
  • Synonyms
    Sirtinol
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SIRT1; SIRT2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    410536-97-9
  • Formula Weight
    394.47
  • Molecular Formula
    C26H22N2O2
  • Purity
    98%
  • Solubility
    DMSO : 6.5 mg/mL 16.48 mM;
  • SMILES
    CC(c1ccccc1)NC(=O)c1ccccc1/N=C/c1c(O)ccc2ccccc12
  • Chemical Name
    2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Grozinger CM, et al. J Biol Chem, 2001, 276(42), 38837-38843.
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