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Sirt2-PROTAC-1
CAS No. 2098487-75-1
Sirt2-PROTAC-1 ( Sirt2-PROTAC-1; Sirt2 PROTAC-1; Sirt2-PROTAC1 )
Catalog No. M13316 CAS No. 2098487-75-1
A novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSirt2-PROTAC-1
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NoteResearch use only, not for human use.
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Brief DescriptionA novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM).
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DescriptionA novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM).
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SynonymsSirt2-PROTAC-1; Sirt2 PROTAC-1; Sirt2-PROTAC1
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC
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Research Area——
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Indication——
Chemical Information
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CAS Number2098487-75-1
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Formula Weight852.94
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Molecular FormulaC40H40N10O8S2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL 117.24 mM; H2O : < 0.1 mg/mL
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SMILESO=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CCCCNC(COC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)N=N3)=C2)S1)CSC7=NC(C)=CC(C)=N7
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Chemical Name2-((4,6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schiedel M, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01872.
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