SirReal1

CAS No. 801227-82-7

SirReal1 ( SirReal 1 )

Catalog No. M15998 CAS No. 801227-82-7

A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SirReal1
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM.
  • Description
    A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM; displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).
  • Synonyms
    SirReal 1
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    Sirtuin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    801227-82-7
  • Formula Weight
    370.49
  • Molecular Formula
    C18H18N4OS2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC1=NC=C(CC2=CC=CC=C2)S1)CSC3=NC(C)=CC(C)=N3
  • Chemical Name
    N-(5-benzylthiazol-2-yl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.
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