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SirReal1

CAS No. 801227-82-7

SirReal1 ( SirReal 1 )

Catalog No. M15998 CAS No. 801227-82-7

A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

SirReal1
Note

Research use only, not for human use.
Brief Description

A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM.
Description

A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM; displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).
Synonyms

SirReal 1
Pathway

Chromatin/Epigenetic
Target

Sirtuin
Recptor

Sirtuin
Research Area

——
Indication

——

Chemical Information

CAS Number

801227-82-7
Formula Weight

370.49
Molecular Formula

C18H18N4OS2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=NC=C(CC2=CC=CC=C2)S1)CSC3=NC(C)=CC(C)=N3
Chemical Name

N-(5-benzylthiazol-2-yl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

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