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Sipatrigine

CAS No. 130800-90-7

Sipatrigine( —— )

Catalog No. M33499 CAS No. 130800-90-7

Sipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.

Purity : >98% (HPLC)

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HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	134	Get Quote
5MG	202	Get Quote
10MG	302	Get Quote
25MG	490	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Sipatrigine
Note

Research use only, not for human use.
Brief Description

Sipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.
Description

Sipatrigine (619C89), a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has the potential in the study for focal cerebral ischemia and stroke.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel | Potassium Channel | Sodium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

130800-90-7
Formula Weight

372.68
Molecular Formula

C15H16Cl3N5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (134.16 mM; Ultrasonic )
SMILES

CN1CCN(CC1)c1ncc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.?

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