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Sinogliatin
CAS No. 1191996-10-7
Sinogliatin( Dorzagliatin | HMS-5552 | RO-5305552 )
Catalog No. M10662 CAS No. 1191996-10-7
Sinogliatin (Dorzagliatin, HMS-5552, RO-5305552) is a novel, first-in-class glucokinase activator (GKS) to treat diabetes mellitus.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSinogliatin
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NoteResearch use only, not for human use.
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Brief DescriptionSinogliatin (Dorzagliatin, HMS-5552, RO-5305552) is a novel, first-in-class glucokinase activator (GKS) to treat diabetes mellitus.
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DescriptionSinogliatin (Dorzagliatin, HMS-5552, RO-5305552) is a novel, first-in-class glucokinase activator (GKS) to treat diabetes mellitus.Diabetes Phase 3 Clinical.
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In Vitro——
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In Vivo——
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SynonymsDorzagliatin | HMS-5552 | RO-5305552
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetGlucokinase
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RecptorGlucokinase
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Research AreaMetabolic Disease
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IndicationDiabetes
Chemical Information
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CAS Number1191996-10-7
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Formula Weight462.93
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Molecular FormulaC22H27ClN4O5
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)C[C@H](N1CC(OC2=CC=CC=C2Cl)=CC1=O)C(NC3=NN(C[C@H](O)CO)C=C3)=O
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Chemical Name(S)-2-(4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(1-((S)-2,3-dihydroxypropyl)-1H-pyrazol-3-yl)-4-methylpentanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Song L, et al. Clin Pharmacokinet. 2018 Oct;57(10):1307-1323.
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Sinogliatin
Sinogliatin (Dorzagliatin, HMS-5552, RO-5305552) is a novel, first-in-class glucokinase activator (GKS) to treat diabetes mellitus.
