Sinapine

CAS No. 18696-26-9

Sinapine( —— )

Catalog No. M18158 CAS No. 18696-26-9

Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 65 In Stock
10MG 102 In Stock
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Biological Information

  • Product Name
    Sinapine
  • Note
    Research use only, not for human use.
  • Brief Description
    Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance.
  • Description
    Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. Sinapine has antioxidant and radio-protective activities.
  • In Vitro
    Sinapine (6 or 60 μM; 1 h) counteracts H2O2 and antimycin A-induced mitochondrial oxidative stress in cardiomyocytes.Sinapine (10-200 μM; 24 h) inhibits the proliferation of Caco-2 cells in a dose-dependent manner, and has relatively low toxicity.Sinapine (10-200 μM; 24 h) promotes doxorubicin accumulation in Caco-2 cell by inducing P-glycoprotein (P-gp) decrease.Sinapine (10-200 μM; 24 h) significantly reduces phosphorylation of FRS2α, ERK1/2.
  • In Vivo
    Sinapine reduces non-alcoholic fatty liver disease in mice by modulating the composition of the gut microbiota.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antioxidant
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    18696-26-9
  • Formula Weight
    310.36
  • Molecular Formula
    C16H24NO5+
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (322.21 mM)
  • SMILES
    C[N+](C)(C)CCOC(=O)C=CC1=CC(=C(C(=C1)OC)O)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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