Silymarin( Silymarin | Milk thistle | Legalon 70 | Flavobion | Wild Artichoke | Silybum marianum )

Catalog No. M15497 CAS No. 65666-07-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Silymarin
Note

Research use only, not for human use.
Brief Description

Silymarin (Silybin B), a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver Y.
Description

Silymarin (Silybin B), a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver Y.
In Vitro

Cell Viability Assay Cell Line:AGS cells Concentration:20 μg/ml, 40 μg/ml, 80 μg/ml, 100 μg/ml and 120 μg/ml Incubation Time:24 hours Result:Indicated a significant concentration-dependent inhibitory effect on AGS cells starting at 20 μg/ml.
In Vivo

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Synonyms

Silymarin | Milk thistle | Legalon 70 | Flavobion | Wild Artichoke | Silybum marianum
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

——

CAS Number

65666-07-1
Formula Weight

482.44
Molecular Formula

C25H22O10
Purity

>98% (HPLC)
Solubility

Ethanol: 1 mg/mL (2.07 mM); DMSO: 97 mg/mL (201.06 mM)
SMILES

COc1c(O)ccc([C@@H]2Oc3c(O[C@H]2CO)ccc([C@H]4Oc5c(C([C@@H]4O)=O)c(O)cc(O)c5)c3)c1
Chemical Name

(2R,3R)-3,5,7-trihydroxy-2-((2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one

1. Feher J, et al. Curr Pharm Biotechnol, 2012, 13(1), 210-217.

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