
Shionone
CAS No. 10376-48-4
Shionone( Shionone | UNII-BT0AMD31UB )
Catalog No. M17771 CAS No. 10376-48-4
Shionone has anti-tussive and anti-inflammatory effects.
Purity : >98% (HPLC)






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Biological Information
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Product NameShionone
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NoteResearch use only, not for human use.
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Brief DescriptionShionone has anti-tussive and anti-inflammatory effects.
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DescriptionShionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections. Shiononeis a tetracyclic triterpenoid is the major triterpenoid component of Aster tataricus possessing a unique all six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure. is perhydrochrysene which is substituted by methyl groups at positions 1, 4bβ, 6aα, 8β, 10aβ and 12a positions, by a 4-methylpent-3-enyl group at the 8α position, and with an oxo group at position 2.
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In Vitro——
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In VivoShionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema. Animal Model:ICR male mice Dosage:80 mg/kg Administration:Orally administration; 3 days; once daily Result:Reduced the ear edema for 11.3% by use shionone.
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SynonymsShionone | UNII-BT0AMD31UB
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number10376-48-4
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Formula Weight426.72
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Molecular FormulaC30H50O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Ethanol : 2 mg/mL (4.69 mM)
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SMILESCC1C(=O)CCC2C1(CCC3C2(CCC4(C3(CCC(C4)(C)CCC=C(C)C)C)C)C)C
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Chemical Name(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog



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