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Sepin-1
CAS No. 163126-81-6
Sepin-1 ( Sepin 1; Sepin1; 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide )
Catalog No. M27925 CAS No. 163126-81-6
Sepin-1 is a noncompetitive inhibitor of separase with an IC50 of 14.8 μM. Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 72 | Get Quote |
|
| 10MG | 115 | Get Quote |
|
| 25MG | 260 | Get Quote |
|
| 50MG | 430 | Get Quote |
|
| 100MG | 620 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSepin-1
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NoteResearch use only, not for human use.
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Brief DescriptionSepin-1 is a noncompetitive inhibitor of separase with an IC50 of 14.8 μM. Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
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DescriptionSepin-1 is a noncompetitive inhibitor of separase with an IC50 of 14.8 μM. Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
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SynonymsSepin 1; Sepin1; 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide
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PathwayOthers
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TargetOther Targets
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RecptorEndogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number163126-81-6
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Formula Weight223.2
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Molecular FormulaC9H9N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1(C)[N+]([O-])=c2ccc(cc2=[N+]1[O-])[N+]([O-])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.P F Li, et al. [Inhibitory effect of 2-(N-acetyl-methyl amino)-3',4'-methylenedioxyacetyl-aminophene(SY-640) on covalent binding of carcinogenic benzo(a)pyrene with mouse hepatocyte nuclear DNA]. Yao Xue Xue Bao. 1997 Sep;32(9):663-8.
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