Senecionine ( Senecionan-1116-dione 12-hydroxy-;Aureine;Senecionin )

Catalog No. M21668 CAS No. 130-01-8

Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Senecionine
Note

Research use only not for human use.
Brief Description

Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.
Description

Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.
Synonyms

Senecionan-1116-dione 12-hydroxy-;Aureine;Senecionin
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

130-01-8
Formula Weight

335.39
Molecular Formula

C18H25NO5
Purity

>98% (HPLC)
Solubility

DMSO: 5 mg/mL (14.91 mM);Ethanol: 1 mg/mL (2.98 mM)
SMILES

C[C@H](C/C(/C(O[C@H](CC1)[C@@H]2N1CC=C2COC1=O)=O)=C/C)[C@@]1(C)O
Chemical Name

(16)Dioxacyclododecino(234-gh)pyrrolizine-27-dione 3-ethylidene-3456911131414a14b-decahydro-6-hydroxy-56-dimethyl- (3Z5R6R14aR14bR)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.D S Griffin et al. Effects of the Pyrrolizidine Alkaloid Senecionine and the Alkenals trans-4-OH-hexenal and trans-2-hexenal on Intracellular Calcium Compartmentation in Isolated Hepatocytes. Biochem Pharmacol. 1989 Feb 1; 38 (3) 391-7

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