Semustine

CAS No. 13909-09-6

Semustine( —— )

Catalog No. M33496 CAS No. 13909-09-6

Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 210 Get Quote
5MG 377 Get Quote
10MG 560 Get Quote
25MG 869 Get Quote
50MG 1178 Get Quote
100MG 1557 Get Quote
500MG 3114 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Semustine
  • Note
    Research use only, not for human use.
  • Brief Description
    Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.
  • Description
    Semustine is a DNA alkylator, binds to DNA, and acts as a cancer chemotherapeutic agent.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA Alkylator/Crosslinker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    13909-09-6
  • Formula Weight
    247.72
  • Molecular Formula
    C10H18ClN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (403.68 mM; Ultrasonic ) Ethanol : 50 mg/mL (201.84 mM; Ultrasonic)
  • SMILES
    N(C(N(CCCl)N=O)=O)C1CCC(C)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Agarwal S, et al. Molecular modeling and spectroscopic studies of semustine binding with DNA and its comparison with lomustine-DNA adduct formation. J Biomol Struct Dyn. 2015;33(8):1653-68.?
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