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Scutellarein

CAS No. 529-53-3

Scutellarein( Scutellarein | 4',5,6,7-Tetrahydroxyflavone )

Catalog No. M17533 CAS No. 529-53-3

Scutellarein reduces inflammatory responses by inhibiting Src kinase activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Scutellarein
  • Note
    Research use only, not for human use.
  • Brief Description
    Scutellarein reduces inflammatory responses by inhibiting Src kinase activity.
  • Description
    Scutellarein is natural product. Scutellarein from Scutellaria barbata induces apoptosis of human colon cancer HCT116 cells through the ROS-mediated mitochondria-dependent pathway. Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity.
  • In Vitro
    ——
  • In Vivo
    Animal Model:HFD mice Dosage:50 mg/kg Administration:in diet, 16 weeks Result:Reduced lipid accumulation and levels of inflammatory factors in the liver.
  • Synonyms
    Scutellarein | 4',5,6,7-Tetrahydroxyflavone
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    GPR
  • Recptor
    Src
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    529-53-3
  • Formula Weight
    286.24
  • Molecular Formula
    C15H10O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 30 mg/mL; 104.81 mM
  • SMILES
    c1cc(ccc1c1cc(=O)c2c(c(c(cc2o1)O)O)O)O
  • Chemical Name
    5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sung NY, et al. Korean J Physiol Pharmacol. 2015 Sep;19(5):441-9.
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