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Scandoside

CAS No. 18842-99-4

Scandoside( —— )

Catalog No. M37776 CAS No. 18842-99-4

Scandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Scandoside
  • Note
    Research use only, not for human use.
  • Brief Description
    Scandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.
  • Description
    Scandoside is a natural product that can be isolated from iridoid glucosides of Paederia scandens.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB | MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    18842-99-4
  • Formula Weight
    390.34
  • Molecular Formula
    C16H22O11
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O([C@H]1[C@]2([C@@](C(C(O)=O)=CO1)([C@H](O)C=C2CO)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Inouye H, et al. Studies on monoterpene glucosides. VII. Iridoid glucosides of Paederia scandens. Chem Pharm Bull (Tokyo). 1969 Sep;17(9):1942-8.?
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