Cart
sales@molnova.com
Scandoside
CAS No. 18842-99-4
Scandoside( —— )
Catalog No. M37776 CAS No. 18842-99-4
Scandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 821 | Get Quote |
|
| 5MG | 1349 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameScandoside
-
NoteResearch use only, not for human use.
-
Brief DescriptionScandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.
-
DescriptionScandoside is a natural product that can be isolated from iridoid glucosides of Paederia scandens.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB | MAPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number18842-99-4
-
Formula Weight390.34
-
Molecular FormulaC16H22O11
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO([C@H]1[C@]2([C@@](C(C(O)=O)=CO1)([C@H](O)C=C2CO)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Inouye H, et al. Studies on monoterpene glucosides. VII. Iridoid glucosides of Paederia scandens. Chem Pharm Bull (Tokyo). 1969 Sep;17(9):1942-8.?
molnova catalog
related products
-
Ganoderic acid H
Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-κB, resulting in the suppression of secretion of uPA.
-
B022
B022 is a selective and potent NF-κB-induced kinase (NIK) inhibitor (Ki: 4.2 nM) and a chemical probe for treating liver inflammation and injury, protecting the liver from inflammation and injury caused by oxidative stress and toxins.
-
Edasalonexent
Edasalonexent (CAT-1004) is a bifunctional, orally administered small molecule that covalently links 2 compounds known to inhibit NF‐κB, salicylic acid and docosahexaenoic acid (DHA).
