Sanguisorbigenin ( 3β-Hydroxyurs-12,19-dien-28-oic acid; Ursa-12,19-dien-28-oic acid; )

Catalog No. M29340 CAS No. 6812-98-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Sanguisorbigenin
Note

Research use only, not for human use.
Brief Description

Sanguisorbigenin is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).
Description

Sanguisorbigenin is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).(In Vitro):Treatment of Sanguisorbigenin with sub-MIC concentrations (1.56-6.25 μg/mL) significantly inhibited the expression of blaR1, mecA, and blaZ in MRSA dose-dependently. The gene expression of mecA is remarkably reduced after the treatment of Sanguisorbigenin. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decreasing PBP2a expression.
Synonyms

3β-Hydroxyurs-12,19-dien-28-oic acid; Ursa-12,19-dien-28-oic acid;
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

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Indication

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CAS Number

6812-98-2
Formula Weight

470.7
Molecular Formula

C30H46O4
Purity

>98% (HPLC)
Solubility

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SMILES

CC1(C)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])C(C)=C(C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
Chemical Name

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