
Salmeterol
CAS No. 89365-50-4
Salmeterol( GR33343X )
Catalog No. M24918 CAS No. 89365-50-4
Salmeterol is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 45 | In Stock |
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10MG | 72 | In Stock |
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25MG | 140 | In Stock |
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50MG | 259 | In Stock |
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100MG | 441 | In Stock |
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200MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameSalmeterol
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NoteResearch use only, not for human use.
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Brief DescriptionSalmeterol is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.
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DescriptionSalmeterol is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.
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In VitroCell Proliferation Assay Cell Line:Human T lymphocytes (THP-1 cells) Concentration:0.001, 0.01, 0.05, 0.2, 1, 5, and 25 μM Incubation Time:Result:The proliferation of Th2 cells was inhibited in a concentration dependent manner.
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In VivoAnimal Model:Male C57BL/6 mice (6-8 weeks old, body weight: 32-35 g)Dosage:Salmeterol (0.16 mg/kg) and/or Formoterol (0.32 mg/kg) Administration:The therapeutic efficacy of co-treatment was investigated in this model over a 56-day-long observation period.Result:COPD assessment test scores were markedly improved in mice with COPD.
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SynonymsGR33343X
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PathwayApoptosis
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TargetAdenosine Receptor
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Recptorβ2-adrenoceptor
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Research Area——
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Indication——
Chemical Information
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CAS Number89365-50-4
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Formula Weight415.57
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Molecular FormulaC25H37NO4
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (240.63 mM)
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SMILESOC1=CC=C(C(O)CNCCCCCCOCCCCC2=CC=CC=C2)C=C1CO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rong, Y., et al., Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol. Biochemistry, 1999. 38(35): p. 11278-86.
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