Salmeterol

CAS No. 89365-50-4

Salmeterol( GR33343X )

Catalog No. M24918 CAS No. 89365-50-4

Salmeterol is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 In Stock
10MG 72 In Stock
25MG 140 In Stock
50MG 259 In Stock
100MG 441 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Salmeterol
  • Note
    Research use only, not for human use.
  • Brief Description
    Salmeterol is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.
  • Description
    Salmeterol is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.
  • In Vitro
    Cell Proliferation Assay Cell Line:Human T lymphocytes (THP-1 cells) Concentration:0.001, 0.01, 0.05, 0.2, 1, 5, and 25 μM Incubation Time:Result:The proliferation of Th2 cells was inhibited in a concentration dependent manner.
  • In Vivo
    Animal Model:Male C57BL/6 mice (6-8 weeks old, body weight: 32-35 g)Dosage:Salmeterol (0.16 mg/kg) and/or Formoterol (0.32 mg/kg) Administration:The therapeutic efficacy of co-treatment was investigated in this model over a 56-day-long observation period.Result:COPD assessment test scores were markedly improved in mice with COPD.
  • Synonyms
    GR33343X
  • Pathway
    Apoptosis
  • Target
    Adenosine Receptor
  • Recptor
    β2-adrenoceptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    89365-50-4
  • Formula Weight
    415.57
  • Molecular Formula
    C25H37NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (240.63 mM)
  • SMILES
    OC1=CC=C(C(O)CNCCCCCCOCCCCC2=CC=CC=C2)C=C1CO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rong, Y., et al., Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol. Biochemistry, 1999. 38(35): p. 11278-86.
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