Salbutamol( AH 3365 | (±)-Salbutamol | DL-Salbutamol )

Catalog No. M12866 CAS No. 18559-94-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Salbutamol
Note

Research use only, not for human use.
Brief Description

Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
Description

Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
In Vitro

Western Blot Analysis Cell Line:MGC803, SGC7901 Concentration:16 μM Incubation Time:24 h Result:Increased β2-AR and ERK levels.Upregulated mesenchymal markers, CDH2 (N-cadherin) and Snail expression, and decreased the expression of epithelial marker CDH1 (E-cadherin).
In Vivo

Animal Model:STZ induced diabetic ratsDosage:6 mg/kg Administration: p.o.Result:Enhanced muscle grip strength, coordination, and antioxidant levels.Reduced proinflammatory markers and oxidative stress. Reduced serum muscle biomarkers. Increased testosterone, restored lipidemic levels, and improved muscle cellular architecture.
Synonyms

AH 3365 | (±)-Salbutamol | DL-Salbutamol
Pathway

Endocrinology/Hormones
Target

Adrenergic Receptor
Recptor

β-adrenergic receptor
Research Area

Neurological Disease
Indication

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1.Brichetto L, et al. Am J Physiol Lung Cell Mol Physiol. 2003 Jan;284(1):L133-9.

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