
SRT3109
CAS No. 1204707-71-0
SRT3109( SRT3109 | SRT-3109 )
Catalog No. M17881 CAS No. 1204707-71-0
SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 167 | In Stock |
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5MG | 255 | In Stock |
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10MG | 380 | In Stock |
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25MG | 619 | In Stock |
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50MG | 861 | In Stock |
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100MG | 1152 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameSRT3109
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NoteResearch use only, not for human use.
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Brief DescriptionSRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.
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DescriptionSRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.
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In VitroSRT3109 (Example 1) is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.
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In Vivo——
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SynonymsSRT3109 | SRT-3109
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PathwayOthers
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TargetOther Targets
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RecptorCXCR2
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number1204707-71-0
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Formula Weight475.53
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Molecular FormulaC18H23F2N5O4S2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL; 210.29 mM
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SMILESC[C@H]([C@H](CO)O)Nc1cc(nc(n1)SCc1c(c(ccc1)F)F)NS(=O)(=O)N1CCC1
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Chemical NameN-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog



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