SRT3109 ( SRT3109; SRT-3109 )

Catalog No. M17881 CAS No. 1204707-71-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

SRT3109
Note

Research use only, not for human use.
Brief Description

SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.
Description

SRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.
Synonyms

SRT3109; SRT-3109
Pathway

Others
Target

Other Targets
Recptor

CXCR2
Research Area

Inflammation/Immunology
Indication

——

CAS Number

1204707-71-0
Formula Weight

475.53
Molecular Formula

C18H23F2N5O4S2
Purity

98%
Solubility

DMSO : ≥ 100 mg/mL; 210.29 mM
SMILES

C[C@H]([C@H](CO)O)Nc1cc(nc(n1)SCc1c(c(ccc1)F)F)NS(=O)(=O)N1CCC1
Chemical Name

N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide