SRI-29329

CAS No. 2086809-58-5

SRI-29329 ( SRI29329;SRI 29329 )

Catalog No. M13252 CAS No. 2086809-58-5

A potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and4, respectively; shows no significant activity for CLK3, CDK1, CDK4 and CDK6 (IC50>1,000 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 178 Get Quote
10MG 291 Get Quote
25MG 492 Get Quote
50MG 709 Get Quote
100MG 972 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SRI-29329
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and4, respectively; shows no significant activity for CLK3, CDK1, CDK4 and CDK6 (IC50>1,000 nM).
  • Description
    A potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and4, respectively; shows no significant activity for CLK3, CDK1, CDK4 and CDK6 (IC50>1,000 nM).
  • Synonyms
    SRI29329;SRI 29329
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CLK
  • Recptor
    CLK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2086809-58-5
  • Formula Weight
    399.93
  • Molecular Formula
    C20H26ClN7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(N1C=NC2=C(NC3=CC=CC(Cl)=C3)N=C(N[C@@H]4[C@@H](N)CCCC4)N=C12)C
  • Chemical Name
    N2-((1S,2S)-2-aminocyclohexyl)-N6-(3-chlorophenyl)-9-isopropyl-9H-purine-2,6-diamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shi Y, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):406-412.
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