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SR8278
CAS No. 1254944-66-5
SR8278 ( —— )
Catalog No. M21127 CAS No. 1254944-66-5
SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM) blocking activation of the receptor by the synthetic agonist GSK 4112.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 112 | In Stock |
|
| 10MG | 177 | In Stock |
|
| 50MG | 414 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSR8278
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NoteResearch use only not for human use.
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Brief DescriptionSR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM) blocking activation of the receptor by the synthetic agonist GSK 4112.
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DescriptionSR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM) blocking activation of the receptor by the synthetic agonist GSK 4112.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorREV-ERBα
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Research Area——
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Indication——
Chemical Information
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CAS Number1254944-66-5
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Formula Weight361.48
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Molecular FormulaC18H19NO3S2
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Purity>98% (HPLC)
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SolubilityDMSO:10mg/ml(27.66mM)
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SMILESCCOC(=O)C1Cc2ccccc2CN1C(=O)c1ccc(SC)s1
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Chemical Nameethyl 2-{[5-(methylsulfanyl)thiophen-2-yl]carbonyl}-1234-tetrahydroisoquinoline-3-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kojetin D Wang Y Kamenecka T M et al. Identification of SR8278 a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB[J]. Acs Chemical Biology 2011 6(2):131-134.
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