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SR17018
CAS No. 2134602-45-0
SR17018( SR17018 | SR-17018 | SR 17018 )
Catalog No. M17433 CAS No. 2134602-45-0
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 58 | In Stock |
|
| 10MG | 87 | In Stock |
|
| 25MG | 192 | In Stock |
|
| 50MG | 312 | In Stock |
|
| 100MG | 507 | In Stock |
|
| 200MG | 707 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSR17018
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NoteResearch use only, not for human use.
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Brief DescriptionSR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
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DescriptionSR17018 is an mu-opioid-receptor (MOR) agonist with an EC50 of 97 nM.
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In VitroSR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. SR17018 shows no obvious effect on inducing βarrestin2 recruitment to the MOR at below 10 μM. SR17018 promotes signaling through G proteins or βarrestin2.
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In Vivo——
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SynonymsSR17018 | SR-17018 | SR 17018
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PathwayMetabolic Enzyme/Protease
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TargetCETP
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Recptorμ-opioid receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number2134602-45-0
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Formula Weight410.72
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Molecular FormulaC19H18Cl3N3O
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Purity>98% (HPLC)
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SolubilityDMSO : 6.4 mg/mL. 15.58 mM;
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SMILESClc3cc4NC(=O)N(C2CCN(Cc1ccc(Cl)cc1)CC2)c4cc3Cl
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Chemical Name5,6-dichloro-1-(1-(4-chlorobenzyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Schmid CL,etal.Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.Cell. 2017 Nov 16;171(5):1165-1175.
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