SPDB

CAS No. 115088-06-7

SPDB ( SPDB, SPDB disulfide heterobifunctional cross-linker )

Catalog No. M10531 CAS No. 115088-06-7

SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 42 In Stock
5MG 77 In Stock
10MG 107 In Stock
50MG 251 In Stock
100MG 341 In Stock
200MG 537 In Stock
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Biological Information

  • Product Name
    SPDB
  • Note
    Research use only, not for human use.
  • Brief Description
    SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).
  • Description
    SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).
  • Synonyms
    SPDB, SPDB disulfide heterobifunctional cross-linker
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    115088-06-7
  • Formula Weight
    326.39
  • Molecular Formula
    C13H14N2O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(ON1C(CCC1=O)=O)CCCSSC2=NC=CC=C2
  • Chemical Name
    Butanoic acid, 4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cumber AJ, et al. Bioconjug Chem. 1992 Sep-Oct;3(5):397-401.
2. Erickson HK, et al. Cancer Res. 2006 Apr 15;66(8):4426-33.
3. Ikeda H, et al. Clin Cancer Res. 2009 Jun 15;15(12):4028-37.
4. Zhao RY, et al. J Med Chem. 2011 May 26;54(10):3606-23.
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