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SPA70

CAS No. 931314-31-7

SPA70( )

Catalog No. M28349 CAS No. 931314-31-7

SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.

SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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50MG 403 Get Quote
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Biological Information

  • Product Name
    SPA70
  • Note
    Research use only, not for human use.
  • Brief Description
    SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.
  • Description
    SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.
  • In Vitro
  • In Vivo
  • Synonyms
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
  • Research Area
  • Indication

Chemical Information

  • CAS Number
    931314-31-7
  • Formula Weight
    415.51
  • Molecular Formula
    C21H25N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 40 mg/mL (96.27 mM)
  • SMILES
    COc1ccc(OC)c(c1)-n1nnc(c1C)S(=O)(=O)c1ccc(cc1)C(C)(C)C
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Huke M, G?rlitzer K, Schenck G. Polyhydroxyaurone. 3. Systematische Charakterisierung durch UV-Spektroskopie und Dünnschicht-Chromatographie [Polyhydroxyaurones. 3. Systematic characterization by UV-spectroscopy and thin layer chromatography]. Arch Pharm Ber Dtsch Pharm Ges. 1969 Jun;302(6):401-22. German.
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