SPA70( —— )

Catalog No. M28349 CAS No. 931314-31-7

SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	115	Get Quote
10MG	165	Get Quote
25MG	263	Get Quote
50MG	403	Get Quote
100MG	592	Get Quote
500MG	1242	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

SPA70
Note

Research use only, not for human use.
Brief Description

SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.
Description

SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

931314-31-7
Formula Weight

415.51
Molecular Formula

C21H25N3O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 40 mg/mL (96.27 mM)
SMILES

COc1ccc(OC)c(c1)-n1nnc(c1C)S(=O)(=O)c1ccc(cc1)C(C)(C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Huke M, G?rlitzer K, Schenck G. Polyhydroxyaurone. 3. Systematische Charakterisierung durch UV-Spektroskopie und Dünnschicht-Chromatographie [Polyhydroxyaurones. 3. Systematic characterization by UV-spectroscopy and thin layer chromatography]. Arch Pharm Ber Dtsch Pharm Ges. 1969 Jun;302(6):401-22. German.

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