SPA70

CAS No. 931314-31-7

SPA70 ( —— )

Catalog No. M28349 CAS No. 931314-31-7

SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 115 Get Quote
10MG 165 Get Quote
25MG 263 Get Quote
50MG 403 Get Quote
100MG 592 Get Quote
500MG 1242 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SPA70
  • Note
    Research use only, not for human use.
  • Brief Description
    SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.
  • Description
    SPA70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    931314-31-7
  • Formula Weight
    415.5
  • Molecular Formula
    C21H25N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccc(OC)c(c1)-n1nnc(c1C)S(=O)(=O)c1ccc(cc1)C(C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Huke M, G?rlitzer K, Schenck G. Polyhydroxyaurone. 3. Systematische Charakterisierung durch UV-Spektroskopie und Dünnschicht-Chromatographie [Polyhydroxyaurones. 3. Systematic characterization by UV-spectroscopy and thin layer chromatography]. Arch Pharm Ber Dtsch Pharm Ges. 1969 Jun;302(6):401-22. German.
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