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SP-13786
CAS No. 1448440-52-5
SP-13786( UAMC-1110 )
Catalog No. M21138 CAS No. 1448440-52-5
SP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 115 | In Stock |
|
| 5MG | 191 | In Stock |
|
| 10MG | 282 | In Stock |
|
| 25MG | 475 | In Stock |
|
| 50MG | 687 | In Stock |
|
| 100MG | 963 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSP-13786
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NoteResearch use only, not for human use.
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Brief DescriptionSP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
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DescriptionSP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
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In Vitro——
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In Vivo——
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SynonymsUAMC-1110
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PathwayOthers
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TargetOther Targets
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RecptorFAP
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Research Area——
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Indication——
Chemical Information
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CAS Number1448440-52-5
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Formula Weight344.32
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Molecular FormulaC17H14F2N4O2
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (290.43 mM; Need ultrasonic)
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SMILESN#CC1CC(F)(F)CN1C(=O)CNC(=O)c1ccnc2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jansen K Heirbaut L Verkerk R et al. Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)[J]. Journal of Medicinal Chemistry 2014 57(7):3053-3074.
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