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SNG-1153
CAS No. 1446712-19-1
SNG-1153( SNG 1153 | SNG1153 )
Catalog No. M11901 CAS No. 1446712-19-1
A derivate of icaritin that inhibits the growth of lung CSCs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 45 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 104 | In Stock |
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| 25MG | 154 | In Stock |
|
| 50MG | 224 | In Stock |
|
| 100MG | 324 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSNG-1153
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NoteResearch use only, not for human use.
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Brief DescriptionA derivate of icaritin that inhibits the growth of lung CSCs.
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DescriptionA derivate of icaritin that inhibits the growth of lung CSCs; inhibits the tumorsphere formation and decreases CD133-positive (lung CSC marker) cancer cells, attenuates tumor formation in NOD/SCID mice; induces β-catenin phosphorylation and down-regulated β-catenin; targets abnormal ERα36 activity, inhibits cell growth and induces apoptosis of BCR-ABL+ leukemic cells, particularly BCR-ABL-T315I mutant cells; effectively eliminates infiltrated BCR-ABL+ blast cells and enhances survival of mice combined with dasatinib.Breast Cancer Preclinical.
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In Vitro——
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In Vivo——
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SynonymsSNG 1153 | SNG1153
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorEstrogen Receptor/ERR
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Research AreaCancer
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IndicationBreast Cancer
Chemical Information
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CAS Number1446712-19-1
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Formula Weight406.3519
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Molecular FormulaC21H17F3O5
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 32 mg/mL
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SMILESO=C1C(O)=C(C2=CC=C(C(F)(F)F)C=C2)OC3=C1C(O)=CC(O)=C3C/C=C(C)\C
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Chemical Name4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-8-(3-methyl-2-buten-1-yl)-2-[4-(trifluoromethyl)phenyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Liu S, et al. Oncotarget. 2016 Jul 19;7(29):45158-45170.
2. Chen M, et al. Oncotarget. 2017 Jul 4;8(27):43662-43677.
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