Cart
sales@molnova.com
Home - Products - Others - Other Targets - SMS2-IN-2

SMS2-IN-2

CAS No. 2241838-28-6

SMS2-IN-2 ( SMS2 inhibitors )

Catalog No. M20666 CAS No. 2241838-28-6

SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 152 In Stock
5MG 259 In Stock
10MG 404 In Stock
25MG 665 In Stock
50MG 888 In Stock
100MG 1251 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SMS2-IN-2
  • Note
    Research use only not for human use.
  • Brief Description
    SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
  • Description
    SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
  • Synonyms
    SMS2 inhibitors
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SMS2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2241838-28-6
  • Formula Weight
    369.78
  • Molecular Formula
    C19H13ClFN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (676.08 mM)
  • SMILES
    Fc1ccc(Cl)c(COc2cccc3onc(Nc4cccnc4)c23)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mo M Yang J Jiang XCet al.Discovery of 4-Benzyloxybenzo[ d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/ db Mice[J].J Med Chem. 2018 Sep 27;61(18):8241-8254.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 2-Amino-2-dichlorobe...

    2-Amino-2-dichlorobenzophenone is a natural compound.

  • Trametenolic acid

    Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.

  • Butein

    Butein, a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.

Sign In Join Free