SMM-295
CAS No. 1054451-22-7
SMM-295 ( SMM295;SMM 295 )
Catalog No. M10252 CAS No. 1054451-22-7
A novel potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSMM-295
-
NoteResearch use only, not for human use.
-
Brief DescriptionA novel potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM.
-
DescriptionA novel potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM, >30-fold selectivity over CB1; reduces cAMP production with a 66-fold selectivity for the CB2 versus the cannabinoid receptor 1 (CB1) in HEK-293 cells; reduces tubular damage and plasma markers of renal dysfunction (i.e., creatinine and NGAL) in acute kidney injury mice.
-
SynonymsSMM295;SMM 295
-
PathwayGPCR/G Protein
-
TargetCannabinoid Receptor
-
RecptorCannabinoid Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1054451-22-7
-
Formula Weight324.44
-
Molecular FormulaC20H20O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name3'-methyl-4-(2-(thiophen-2-yl)propan-2-yl)-[1,1'-biphenyl]-2,6-diol
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Pressly JD, et al. J Pharmacol Exp Ther. 2017 Nov 29. pii: jpet.117.245522.
molnova catalog
related products
-
NESS-040C5
A potent, reasonably selective cannabinoid CB2 agonist with Ki of 0.4 nM, 25-fold selectivity over CB1 receptor.
-
JTE907
A potent, selective, orally active cannabinoid CB2 receptor inverse agonist with Ki of 35.9, 1.55 and 0.38 nM for human, mouse and rat CB2, respectively.
-
Repertaxin
Reparixin is a potent inhibitor of both CXCL8 receptorsCXCR1/2, it inhibits weaklyCXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocksCXCR1-mediated chemotaxis (IC50=1 nM).