SM-2470( —— )

Catalog No. M35679 CAS No. 99899-45-3

SM-2470 is an α1-adrenoceptor antagonist with antihypertensive activity that decreases anterior ganglionic adrenal nerve activity and aortic descending nerve activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

SM-2470
Note

Research use only, not for human use.
Brief Description

SM-2470 is an α1-adrenoceptor antagonist with antihypertensive activity that decreases anterior ganglionic adrenal nerve activity and aortic descending nerve activity.
Description

SM-2470 is a potent α1-adrenoceptor antagonist, has sympathetic nerve activity in anesthetized rats. SM-2470 is an antihypertensive agent. SM-2470 exhibits hypocholesterolaemic effect by the inhibition of cholesterol absorption related to the reduction of cholesterol solubilization.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Adrenergic Receptor
Recptor

Adrenergic Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

99899-45-3
Formula Weight

459.97
Molecular Formula

C23H30ClN5O3
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.O=C(N1CCN(C=2N=C(N)C=3C=C(OC)C(OC)=CC3N2)CC1)C4CC5C=CC4CC5
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. M Yoshioka, et al. Effect of SM-2470, a newly synthetized alpha 1-adrenoceptor antagonist, on sympathetic nerve activity in anesthetized rats. Arch Int Pharmacodyn Ther. May-Jun 1988;293:162-74.?

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