SLC26A3-IN-2

Research use only, not for human use.

SLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, with an IC50 of 360 nM.

SLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC50=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea.

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Others

Other Targets

Others

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950348-60-4

368.84

C19H13ClN2O2S

>98% (HPLC)

In Vitro:?DMSO : 16.67 mg/mL (45.20 mM; Ultrasonic (<60°C)

O=C1N2C(=CSC2=NC(COC3=C(Cl)C=CC=C3)=C1)C4=CC=CC=C4

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(-20℃)

With Ice Pack

≥ 2 years