SKA31 ( SKA 31;SKA-31;Naphtho[12-d]thiazol-2-ylamine )

Catalog No. M20078 CAS No. 40172-65-4

SKA 31 is an activator of KCa3.1 and KCa2 channels (EC50s: 260 2900 2900 nM for KCa3.1 KCa2.1 and KCa2.2 respectively).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

SKA31
Note

Research use only not for human use.
Brief Description

SKA 31 is an activator of KCa3.1 and KCa2 channels (EC50s: 260 2900 2900 nM for KCa3.1 KCa2.1 and KCa2.2 respectively).
Description

SKA 31 is an activator of KCa3.1 and KCa2 channels (EC50s: 260 2900 2900 nM for KCa3.1 KCa2.1 and KCa2.2 respectively).
Synonyms

SKA 31;SKA-31;Naphtho[12-d]thiazol-2-ylamine
Pathway

Cell Cycle/DNA Damage
Target

Potassium Channel
Recptor

KCa3.1 channel
Research Area

——
Indication

——

Chemical Information

CAS Number

40172-65-4
Formula Weight

200.26
Molecular Formula

C11H8N2S
Purity

>98% (HPLC)
Solubility

DMSO: 30 mg/mL (150 mM)
SMILES

Nc1nc2c(ccc3ccccc23)s1
Chemical Name

Naphtho[12-d]thiazol-2-ylamine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Sankaranarayanan A Naphtho[12-d]thiazol-2-ylamine (SKA-31) a new activator of KCa2 and KCa3.1 potassium channels potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure. Mol Pharmacol. 2009 Feb;75(2):281-95.

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