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SKA31
CAS No. 40172-65-4
SKA31 ( SKA 31;SKA-31;Naphtho[12-d]thiazol-2-ylamine )
Catalog No. M20078 CAS No. 40172-65-4
SKA 31 is an activator of KCa3.1 and KCa2 channels (EC50s: 260 2900 2900 nM for KCa3.1 KCa2.1 and KCa2.2 respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 50 | In Stock |
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| 10MG | 72 | In Stock |
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| 25MG | 147 | In Stock |
|
| 50MG | 290 | In Stock |
|
| 100MG | 515 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSKA31
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NoteResearch use only not for human use.
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Brief DescriptionSKA 31 is an activator of KCa3.1 and KCa2 channels (EC50s: 260 2900 2900 nM for KCa3.1 KCa2.1 and KCa2.2 respectively).
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DescriptionSKA 31 is an activator of KCa3.1 and KCa2 channels (EC50s: 260 2900 2900 nM for KCa3.1 KCa2.1 and KCa2.2 respectively).
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SynonymsSKA 31;SKA-31;Naphtho[12-d]thiazol-2-ylamine
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorKCa3.1 channel
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Research Area——
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Indication——
Chemical Information
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CAS Number40172-65-4
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Formula Weight200.26
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Molecular FormulaC11H8N2S
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Purity>98% (HPLC)
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SolubilityDMSO: 30 mg/mL (150 mM)
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SMILESNc1nc2c(ccc3ccccc23)s1
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Chemical NameNaphtho[12-d]thiazol-2-ylamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sankaranarayanan A Naphtho[12-d]thiazol-2-ylamine (SKA-31) a new activator of KCa2 and KCa3.1 potassium channels potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure. Mol Pharmacol. 2009 Feb;75(2):281-95.
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