SHP099

CAS No. 1801747-42-1

SHP099 ( SHP099 free base; SHP099; SHP-099; SHP 099 )

Catalog No. M28048 CAS No. 1801747-42-1

SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 40 Get Quote
5MG 65 Get Quote
10MG 91 Get Quote
25MG 159 Get Quote
50MG 213 Get Quote
100MG 388 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SHP099
  • Note
    Research use only, not for human use.
  • Brief Description
    SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
  • Description
    SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
  • Synonyms
    SHP099 free base; SHP099; SHP-099; SHP 099
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1801747-42-1
  • Formula Weight
    352.3
  • Molecular Formula
    C16H19Cl2N5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1(N)CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Smith JL, et al. Fusarium graminearum Mycotoxins in Maize Associated With Striacosta albicosta (Lepidoptera: Noctuidae) Injury. J Econ Entomol. 2018 Mar 14.
molnova catalog
related products
  • Abyssinone V

    Abyssinone V is a natural compound isolated from the stem bark of Erythrina melanacantha and an inhibitor of protein tyrosine phosphatase-1B (PTP1B).

  • PTP1B-IN-4

    PTP1B-IN-4 is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.

  • SHIP2-IN-1

    SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.