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SHP099
CAS No. 1801747-42-1
SHP099( SHP099 free base | SHP099 | SHP-099 | SHP 099 )
Catalog No. M28048 CAS No. 1801747-42-1
SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | Get Quote |
|
| 5MG | 65 | Get Quote |
|
| 10MG | 91 | Get Quote |
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| 25MG | 159 | Get Quote |
|
| 50MG | 213 | Get Quote |
|
| 100MG | 388 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSHP099
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NoteResearch use only, not for human use.
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Brief DescriptionSHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
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DescriptionSHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
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In Vitro——
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In Vivo——
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SynonymsSHP099 free base | SHP099 | SHP-099 | SHP 099
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorAntifungal
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Research Area——
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Indication——
Chemical Information
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CAS Number1801747-42-1
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Formula Weight352.26
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Molecular FormulaC16H19Cl2N5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 12 mg/mL (34.07 mM)
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SMILESCC1(N)CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Smith JL, et al. Fusarium graminearum Mycotoxins in Maize Associated With Striacosta albicosta (Lepidoptera: Noctuidae) Injury. J Econ Entomol. 2018 Mar 14.
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