SGN-2FF
CAS No. 2089647-47-0
SGN-2FF ( —— )
Catalog No. M26438 CAS No. 2089647-47-0
SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 147 | Get Quote |
|
10MG | 260 | Get Quote |
|
25MG | 520 | Get Quote |
|
50MG | 709 | Get Quote |
|
100MG | 1008 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSGN-2FF
-
NoteResearch use only, not for human use.
-
Brief DescriptionSGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
-
DescriptionSGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.(In Vitro):SGN-2FF is a fucosylation inhibitor, SGN-2FF inhibits cellular fucosylation by depleting the fucosylation substrate GDP-fucose, and by direct inhibition of fucosyltransferases, and leads to the production of fucosylated glycoproteins including antibodies. SGN-2FF activates human T cells in an antigen-dependent manner.(In Vivo):In multiple mouse tumor models, SGN-2FF exhibits antitumor activity. SGN-2FF shows substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorTelomerase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2089647-47-0
-
Formula Weight166.1
-
Molecular FormulaC6H11FO4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC[C@@H]1OC(O)[C@@H](F)[C@H](O)[C@@H]1O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Quan Wang J, et al. Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1199-1211.
molnova catalog
related products
-
Ac-IEVDIDVEH (TFA)
Ac-IEVDIDVEH TFA is a short peptide sequence with Ac at the end.
-
Thalidomide-NH-CH2-C...
Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
-
Pentagastrin
pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins.