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SGN-2FF
CAS No. 2089647-47-0
SGN-2FF ( —— )
Catalog No. M26438 CAS No. 2089647-47-0
SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 147 | Get Quote |
|
| 10MG | 260 | Get Quote |
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| 25MG | 520 | Get Quote |
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| 50MG | 709 | Get Quote |
|
| 100MG | 1008 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSGN-2FF
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NoteResearch use only, not for human use.
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Brief DescriptionSGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
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DescriptionSGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.(In Vitro):SGN-2FF is a fucosylation inhibitor, SGN-2FF inhibits cellular fucosylation by depleting the fucosylation substrate GDP-fucose, and by direct inhibition of fucosyltransferases, and leads to the production of fucosylated glycoproteins including antibodies. SGN-2FF activates human T cells in an antigen-dependent manner.(In Vivo):In multiple mouse tumor models, SGN-2FF exhibits antitumor activity. SGN-2FF shows substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTelomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number2089647-47-0
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Formula Weight166.1
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Molecular FormulaC6H11FO4
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@@H]1OC(O)[C@@H](F)[C@H](O)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Quan Wang J, et al. Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1199-1211.
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