Cart
sales@molnova.com
SGC-CBP30
CAS No. 1613695-14-9
SGC-CBP30( SGC-CBP30 | SGC-CBP 30 | SGC-CBP-30 )
Catalog No. M17342 CAS No. 1613695-14-9
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 59 | In Stock |
|
| 5MG | 72 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 200 | In Stock |
|
| 50MG | 335 | In Stock |
|
| 100MG | 500 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSGC-CBP30
-
NoteResearch use only, not for human use.
-
Brief DescriptionSGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
-
DescriptionSGC-CBP30 is a potent and selective inhibitor of CREBBP (CBP) and EP300; which are general transcriptional co-activators. CREBBP has also been associated with Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig?’s disease, a neurodegenerative disease with progressive degeneration of motor neurons in the brain and spinal cord, Alzheimer's disease and poly glutamine repeat diseases such as Spinal and Bulbar Muscular Atrophy and Huntington?’s disease.
-
In Vitro——
-
In VivoAnimal Model:Sprague-Dawley (SD) rats (aged 3-4 weeks) injected with NSC-125066 Dosage:25 mg/kg Administration:Oral administration; daily; for 14 days Result:Slightly alleviated alveolar bronchial fibrosis induced by NSC-125066.
-
SynonymsSGC-CBP30 | SGC-CBP 30 | SGC-CBP-30
-
PathwayOthers
-
TargetOther Targets
-
RecptorCREBBP| EP300
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1613695-14-9
-
Formula Weight509.04
-
Molecular FormulaC28H33CIN4O3
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 31 mg/mL; 60.90 mM
-
SMILESCc1noc(C)c1c1cc2nc(CCc3ccc(OC)c(Cl)c3)n(C[C@H](C)N3CCOCC3)c2cc1
-
Chemical Name(S)-4-(1-(2-(3-chloro-4-methoxyphenethyl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-1-yl)propan-2-yl)morpholine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Structural Genomics Consortium
molnova catalog
related products
-
QS-21
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells.
-
Bryonolic acid
Bryonolic acid is a triterpenoid found in the Cucurbitaceae family of plants. Bryonolic acid has anti-inflammatory and antioxidant activities. It has been found to exhibit antineoplastic activity.
-
Sulfopin
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
