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SEA-0400
CAS No. 223104-29-8
SEA-0400 ( SEA0400; SEA-0400; SEA 0400 )
Catalog No. M17444 CAS No. 223104-29-8
SEA0400 is a selective inhibitor of the Na+/Ca2+exchanger.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 41 | In Stock |
|
| 5MG | 67 | In Stock |
|
| 10MG | 120 | In Stock |
|
| 25MG | 219 | In Stock |
|
| 50MG | 357 | In Stock |
|
| 100MG | 537 | In Stock |
|
| 500MG | 1188 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSEA-0400
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NoteResearch use only, not for human use.
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Brief DescriptionSEA0400 is a selective inhibitor of the Na+/Ca2+exchanger.
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DescriptionSEA0400 is a Na+/Ca2+ exchanger 1 inhibitor. SEA0400 prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. SEA0400 reduces calcium overload induced by ischemia and reperfusion in mouse ventricular myocytes. SEA0400 attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia. SEA0400, preserves cardiac function and high-energy phosphates against ischemia/reperfusion injury.
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SynonymsSEA0400; SEA-0400; SEA 0400
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PathwayOthers
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TargetOther Targets
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RecptorNCX
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number223104-29-8
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Formula Weight371.38
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Molecular FormulaC21H19F2NO3
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Purity98%
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SolubilityDMSO : ≥ 32 mg/mL; 86.17 mM
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SMILESCCOc1cc(c(cc1)Oc1ccc(cc1)OCc1c(ccc(c1)F)F)N
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Chemical Name2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Matsuda, T., et al. J.Pharmacol.Exp.Ther. 2001, 298(1), 249-256.
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