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SEA-0400

CAS No. 223104-29-8

SEA-0400 ( SEA0400; SEA-0400; SEA 0400 )

Catalog No. M17444 CAS No. 223104-29-8

SEA0400 is a selective inhibitor of the Na+/Ca2+exchanger.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 67 In Stock
10MG 120 In Stock
25MG 219 In Stock
50MG 357 In Stock
100MG 537 In Stock
500MG 1188 In Stock
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Biological Information

  • Product Name
    SEA-0400
  • Note
    Research use only, not for human use.
  • Brief Description
    SEA0400 is a selective inhibitor of the Na+/Ca2+exchanger.
  • Description
    SEA0400 is a Na+/Ca2+ exchanger 1 inhibitor. SEA0400 prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. SEA0400 reduces calcium overload induced by ischemia and reperfusion in mouse ventricular myocytes. SEA0400 attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia. SEA0400, preserves cardiac function and high-energy phosphates against ischemia/reperfusion injury.
  • Synonyms
    SEA0400; SEA-0400; SEA 0400
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NCX
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    223104-29-8
  • Formula Weight
    371.38
  • Molecular Formula
    C21H19F2NO3
  • Purity
    98%
  • Solubility
    DMSO : ≥ 32 mg/mL; 86.17 mM
  • SMILES
    CCOc1cc(c(cc1)Oc1ccc(cc1)OCc1c(ccc(c1)F)F)N
  • Chemical Name
    2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Matsuda, T., et al. J.Pharmacol.Exp.Ther. 2001, 298(1), 249-256.
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