Cart
sales@molnova.com
SCYX-7158
CAS No. 1266084-51-8
SCYX-7158 ( AN-5568;SCYX 7158;AN 5568;Acoziborole )
Catalog No. M11117 CAS No. 1266084-51-8
SCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 260 | Get Quote |
|
| 50MG | 1188 | Get Quote |
|
| 100MG | 1791 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSCYX-7158
-
NoteResearch use only, not for human use.
-
Brief DescriptionSCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent.
-
DescriptionSCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent; is active in vitro against relevant strains of Trypanosoma brucei, including T. b. rhodesiense and T. b. gambiense; is efficacious in both stage 1 and stage 2 murine HAT models and has good physicochemical and ADMET properties for the treatment of stage 2 human African trypanosomiasis.Parasite Infection Phase 3 Clinical
-
SynonymsAN-5568;SCYX 7158;AN 5568;Acoziborole
-
PathwayMicrobiology/Virology
-
TargetParasite
-
RecptorParasite
-
Research AreaInfection
-
IndicationParasite Infection
Chemical Information
-
CAS Number1266084-51-8
-
Formula Weight367.10
-
Molecular FormulaC17H14BF4NO3
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 125 mg/mL 340.51 mM
-
SMILESFC1=CC(C(F)(F)F)=C(C(NC2=CC=C(C(C)(C)OB3O)C3=C2)=O)C=C1
-
Chemical Name4-fluoro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-(trifluoromethyl)benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jacobs RT, et al. PLoS Negl Trop Dis. 2011 Jun;5(6):e1151.
2. Jacobs RT, et al. Future Med Chem. 2011 Aug;3(10):1259-78.
3. Wring S, et al. Parasitology. 2014 Jan;141(1):104-18.
2. Jacobs RT, et al. Future Med Chem. 2011 Aug;3(10):1259-78.
3. Wring S, et al. Parasitology. 2014 Jan;141(1):104-18.
molnova catalog
related products
-
Oxysanguinarine
Oxysanguinarine possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.
-
MBP146-78
MBP146-78 is a potent and selective cGMP inhibitor dependent protein kinases.
-
Cipargamin
Cipargamin (KAE609, NITD609) is a fast-acting, potent antimalarial agent that inhibits blood-stage activity in vitro against a panel of culture-adapted P. falciparum strains with IC50 of 0.5-1.4 nM.
