SC-560

CAS No. 188817-13-2

SC-560 ( SC-560; SC 560; SC560 )

Catalog No. M17399 CAS No. 188817-13-2

SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 30 In Stock
5MG 47 In Stock
10MG 84 In Stock
25MG 178 In Stock
50MG 227 In Stock
100MG 291 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SC-560
  • Note
    Research use only, not for human use.
  • Brief Description
    SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
  • Description
    SC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.
  • Synonyms
    SC-560; SC 560; SC560
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    COX-1; COX-2
  • Research Area
    Cancer|Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    188817-13-2
  • Formula Weight
    352.74
  • Molecular Formula
    C17H12ClF3N2O
  • Purity
    98%
  • Solubility
    DMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL
  • SMILES
    COc1ccc(cc1)n1c(cc(n1)C(F)(F)F)c1ccc(cc1)Cl
  • Chemical Name
    5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13313-8.
molnova catalog
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