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SC-560

CAS No. 188817-13-2

SC-560 ( SC-560; SC 560; SC560 )

Catalog No. M17399 CAS No. 188817-13-2

SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 30 In Stock
5MG 47 In Stock
10MG 84 In Stock
25MG 178 In Stock
50MG 227 In Stock
100MG 291 In Stock
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Biological Information

  • Product Name
    SC-560
  • Note
    Research use only, not for human use.
  • Brief Description
    SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
  • Description
    SC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.
  • Synonyms
    SC-560; SC 560; SC560
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    COX-1; COX-2
  • Research Area
    Cancer|Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    188817-13-2
  • Formula Weight
    352.74
  • Molecular Formula
    C17H12ClF3N2O
  • Purity
    98%
  • Solubility
    DMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL
  • SMILES
    COc1ccc(cc1)n1c(cc(n1)C(F)(F)F)c1ccc(cc1)Cl
  • Chemical Name
    5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13313-8.
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