SBI-425( —— )

Catalog No. M26818 CAS No. 1451272-71-1

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

SBI-425
Note

Research use only, not for human use.
Brief Description

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP).
Description

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival without a detectable change in the bone.
In Vitro

SBI-425 treatment suppresses Foxp3 expression in CD4+ and CD8+ T cells in splenocytes from CLP-injured mice.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

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Chemical Information

CAS Number

1451272-71-1
Formula Weight

341.77
Molecular Formula

C13H12ClN3O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 86.67 mg/mL (253.59 mM)
SMILES

COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.A L Tarentino, et al. 2-Iminothiolane: a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycans. Glycobiology. 1993 Jun;3(3):279-85.

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