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SBI-425

CAS No. 1451272-71-1

SBI-425( —— )

Catalog No. M26818 CAS No. 1451272-71-1

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 107 Get Quote
25MG 173 Get Quote
50MG 252 Get Quote
100MG 374 Get Quote
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Biological Information

  • Product Name
    SBI-425
  • Note
    Research use only, not for human use.
  • Brief Description
    SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP).
  • Description
    SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival without a detectable change in the bone.
  • In Vitro
    SBI-425 treatment suppresses Foxp3 expression in CD4+ and CD8+ T cells in splenocytes from CLP-injured mice.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1451272-71-1
  • Formula Weight
    341.77
  • Molecular Formula
    C13H12ClN3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 86.67 mg/mL (253.59 mM)
  • SMILES
    COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.A L Tarentino, et al. 2-Iminothiolane: a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycans. Glycobiology. 1993 Jun;3(3):279-85.
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