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SBC-115076
CAS No. 489415-96-5
SBC-115076( SBC-115076 | SBC 115076 | SBC115076. )
Catalog No. M17523 CAS No. 489415-96-5
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 43 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 91 | In Stock |
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| 25MG | 171 | In Stock |
|
| 50MG | 309 | In Stock |
|
| 100MG | 478 | In Stock |
|
| 500MG | 1062 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSBC-115076
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NoteResearch use only, not for human use.
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Brief DescriptionSBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
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DescriptionSBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
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In Vitro——
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In VivoAnimal Model:Female Wistar rats (high-fat diet (HFD)- fed) Dosage:4 mg/kg Administration:S.c.; daily for 3 weeks Result:Superior to atorvastatin in instigating weight loss, cholesterol reduction, and attenuation of mitochondrial oxidative stress in oxidative muscle fibers of obese female rats.
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SynonymsSBC-115076 | SBC 115076 | SBC115076.
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PathwayTyrosine Kinase
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TargetSrc
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RecptorPCSK9
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number489415-96-5
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Formula Weight527.61
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Molecular FormulaC31H33N3O5
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 32 mg/mL; 60.65 mM
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SMILESCc1cc(C(=O)C2=C(O)C(=O)N(C2c2ccncc2)CCCN2CCOCC2)ccc1OCc1ccccc1
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Chemical Name4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Abdel-Meguid SS, et al. WO2014150326 A1.
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