Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - 5-HT Receptor - SB-258585

SB-258585

CAS No. 209480-63-7

SB-258585( SB258585 )

Catalog No. M13292 CAS No. 209480-63-7

SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 86 Get Quote
10MG 147 Get Quote
25MG 264 Get Quote
50MG 464 Get Quote
100MG 664 Get Quote
500MG 1377 Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SB-258585
  • Note
    Research use only, not for human use.
  • Brief Description
    SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.
  • Description
    SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes; also is an inhibitor of HCV entry in liver-derived cell lines as well as primary hepatocytes, modulates localization of the coreceptor tight junction protein claudin-1 (CLDN1) in a 5-HT6-independent manner, induces intracellular accumulation of CLDN1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SB258585
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    209480-63-7
  • Formula Weight
    487.356
  • Molecular Formula
    C18H22IN3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O.[H]Cl
  • Chemical Name
    4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hirst WD, et al. Br J Pharmacol. 2000 Aug;130(7):1597-605. 2. Riva L, et al. J Virol. 2018 Apr 27;92(10). pii: e01982-17.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Rizatriptan benzoate

    Rizatriptan Benzoate(Maxalt) is a?5-HT1 agonist triptan?drug for the treatment of migraine headaches.

  • Chlorprothixene hydr...

    Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class.

  • Citalopram HBr

    Citalopram hydrobromide belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).

Sign In Join Free