Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Neurokinin Receptor - SB-222200

SB-222200

CAS No. 174635-69-9

SB-222200 ( —— )

Catalog No. M23788 CAS No. 174635-69-9

SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 61 In Stock
10MG 93 In Stock
25MG 228 In Stock
50MG 437 In Stock
100MG 624 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SB-222200
  • Note
    Research use only, not for human use.
  • Brief Description
    SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM).
  • Description
    SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM).
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Neurokinin Receptor
  • Recptor
    NK3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    174635-69-9
  • Formula Weight
    380.5
  • Molecular Formula
    C26H24N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (262.83 mM)
  • SMILES
    O=C(C1=C(C)C(C2=CC=CC=C2)=NC3=CC=CC=C13)N[C@H](C4=CC=CC=C4)CC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sarau HM, et al. Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist. J Pharmacol Exp Ther. 2000 Oct;295(1):373-81.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Kassinin

    Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides.

  • Neurokinin B

    Neurokinin B (NKB) belongs in the family of tachykinin peptides. Neurokinin B is implicated in a variety of human functions and pathways such as the secretion of gonadotropin-releasing hormone.

  • MLE-4901

    A potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of schizophrenia.

Sign In Join Free