S107

CAS No. 927871-76-9

S107 ( —— )

Catalog No. M17667 CAS No. 927871-76-9

S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 In Stock
5MG 87 In Stock
10MG 132 In Stock
25MG 240 In Stock
50MG 402 In Stock
100MG 573 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    S107
  • Note
    Research use only, not for human use.
  • Brief Description
    S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
  • Description
    S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    927871-76-9
  • Formula Weight
    209.31
  • Molecular Formula
    C11H15NOS
  • Purity
    98%
  • Solubility
    DMSO : ≥ 38 mg/mL; 181.55 mM
  • SMILES
    CN1CCSc2c(C1)cc(cc2)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lehnart SE, et al. J Clin Invest. 2008 Jun;118(6):2230-45.
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