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S0859

CAS No. 1019331-10-2

S0859( S0859 | S-0859 | S 0859. )

Catalog No. M10093 CAS No. 1019331-10-2

S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    S0859
  • Note
    Research use only, not for human use.
  • Brief Description
    S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery.
  • Description
    S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM).
  • In Vitro
    Treatment with NBC inhibitor S0859 significantly increased caspase-3 activity and elevated the number of apoptotic EC. S0859 is potentially important for probing the transporter's functional role in heart and other tissues.
  • In Vivo
    ——
  • Synonyms
    S0859 | S-0859 | S 0859.
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NBC
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1019331-10-2
  • Formula Weight
    530.04
  • Molecular Formula
    C29H24ClN3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl
  • Chemical Name
    2-chloro-N-((2'-(N-cyanosulfamoyl)-[1,1'-biphenyl]-4-yl)methyl)-N-(4-methylbenzyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Larsen AM, et al. ChemMedChem. 2012 Oct;7(10):1808-14.
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