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S0859
CAS No. 1019331-10-2
S0859( S0859 | S-0859 | S 0859. )
Catalog No. M10093 CAS No. 1019331-10-2
S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
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| 5MG | 47 | In Stock |
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| 10MG | 80 | In Stock |
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| 25MG | 164 | In Stock |
|
| 50MG | 300 | In Stock |
|
| 100MG | 473 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameS0859
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NoteResearch use only, not for human use.
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Brief DescriptionS0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery.
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DescriptionS0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM).
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In VitroTreatment with NBC inhibitor S0859 significantly increased caspase-3 activity and elevated the number of apoptotic EC. S0859 is potentially important for probing the transporter's functional role in heart and other tissues.
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In Vivo——
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SynonymsS0859 | S-0859 | S 0859.
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PathwayOthers
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TargetOther Targets
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RecptorNBC
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number1019331-10-2
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Formula Weight530.04
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Molecular FormulaC29H24ClN3O3S
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl
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Chemical Name2-chloro-N-((2'-(N-cyanosulfamoyl)-[1,1'-biphenyl]-4-yl)methyl)-N-(4-methylbenzyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Larsen AM, et al. ChemMedChem. 2012 Oct;7(10):1808-14.
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