S-Gboxin

CAS No. 2101317-21-7

S-Gboxin( —— )

Catalog No. M20091 CAS No. 2101317-21-7

S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM IC50: 470 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 215 In Stock
10MG 312 In Stock
25MG 530 In Stock
50MG 758 In Stock
100MG 1044 In Stock
500MG 2097 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    S-Gboxin
  • Note
    Research use only, not for human use.
  • Brief Description
    S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM IC50: 470 nM).
  • Description
    S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM IC50: 470 nM).
  • In Vitro
    ——
  • In Vivo
    S-Gboxin retains excellent metabolic stability, enhanced plasma stability, and PK-propertiessuitable for in vivo studies. S-Gboxin (10 mg/kg/day; intraperitoneally) inhibits glioblastoma (GBM) growth in vivo. Animal Model:Female nude mice (6 to 9 weeks)Dosage:10 mg/kg/day Administration:Administered intraperitoneally; daily; 3 or 14 days Result:Resulted in significant attenuation of growth and decreased cellular density compared to controls.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2101317-21-7
  • Formula Weight
    600.46
  • Molecular Formula
    C27H32F3IN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 85 mg/mL (141.56 mM)
  • SMILES
    [I-].CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)Cn1c(-c2cccc(c2)C(F)(F)F)[n+](C)c2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shi Y et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346.
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