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Rubropunctamine

CAS No. 514-66-9

Rubropunctamine( —— )

Catalog No. M21783 CAS No. 514-66-9

Rubropunctamine is a red azaphilone pigment isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctamine has anti-inflammation activities.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Rubropunctamine
  • Note
    Research use only, not for human use.
  • Brief Description
    Rubropunctamine is a red azaphilone pigment isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctamine has anti-inflammation activities.
  • Description
    Rubropunctamine is a red azaphilone pigment isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctamine has anti-inflammation activities.
  • In Vitro
    Rubropunctamine (0.32-32 nM; 48 h) inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), with an IC50 of 433 mol ratio/32 pmol TPA.Rubropunctamine (1 h) exhibits moderate scavenging activity (inhibitory ratio (IR)=1.5) against NO generation by (±)-(E)-methyl-2[(E)-hydroxy-imino]-5-nitro-6-methoxy-3-hexemide (NOR 1) in normal human hepato cells.
  • In Vivo
    Rubropunctamine inhibits TPA-induced inflammation in mice, with an ID50 of 0.32 mg/ear.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    514-66-9
  • Formula Weight
    353.41
  • Molecular Formula
    C??H??NO?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1O[C@]2(C)C(C=C3C(C2=O)=CNC(/C=C/C)=C3)=C1C(CCCCC)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Akihisa T, et, al. Azaphilones, furanoisophthalides, and amino acids from the extracts of Monascus pilosus-fermented rice (red-mold rice) and their chemopreventive effects. J Agric Food Chem. 2005 Feb 9;53(3):562-5. 2. Patakova P. Monascus secondary metabolites: production and biological activity. J Ind Microbiol Biotechnol. 2013 Feb;40(2):169-81.
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