Rosmantuzumab( —— )

Catalog No. M37100 CAS No. 1684393-04-1

Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	347	Get Quote
5MG	560	Get Quote
10MG	911	Get Quote
25MG	1306	Get Quote
50MG	1766	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Rosmantuzumab
Note

Research use only, not for human use.
Brief Description

Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3).
Description

Rosmantuzumab (OMP-131R10) is an anti-R-spondin 3 (RSPO3) humanized monoclonal antibody. Rosmantuzumab can be used for the research of advanced telapsed and refractory solid tumors.
In Vitro

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In Vivo

Animal Model:Male C57B1/6J CCl4 liver fibrosis mouse models Dosage:25 mg/kg Administration:Intraperitoneal injection; 25 mg/kg, once a week for 4 weeks Result:Significantly decreased collagen I and collagen III mRNAs, and inhibits β-catenin cytoplasmic and nuclear translocation.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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Chemical Information

CAS Number

1684393-04-1
Formula Weight
Molecular Formula

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Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Zhang M, et al. Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. PLoS One. 2020 Mar 11;15(3):e0229445.?

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